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Metabolic effects occurring during anabolic steroid therapy in immobilized patients or those with metastatic breast disease include osteolytic-induced hypercalcemia .

Anabolic steroids effect electrolyte balance, nitrogen retention, and urinary calcium excretion. Edema, with and without congestive heart failure, has occurred during anabolic steroid therapy.

The androgenic activity of anabolic steroids may decrease levels of thyroxin-binding globulin, resulting in decreased total T4 serum levels and increased resin uptake of T3 and T4. Free thyroid hormone levels remain unchanged, however, and there is no clinical evidence of thyroid dysfunction.

Significant increases in low density lipoproteins (LDL) and decreases in high density lipoproteins (HDL) have occurred. [ Ref ]

Water based or Aqueous testosterone suspension can peak in the blood stream within minutes of being injected and is metabolized very fast. Because Testosterone Suspension remains in the body for a short time, it has to be injected very frequently. In most cases Testosterone Suspension has to be administered daily or few times a day in order to maintain a stable blood testosterone level. If  Testosterone Suspension  is your preferred choice you can rotate injection spots each time rather than injecting the same location each day. This form of testosterone is not highly recommended and is often used by very experienced and extreme athletes, body builders and power-lifters. This testosterone form give the best strength results and a high aggressiveness. It also exist a testosterone with no ester and oil based called TNE (Testosterone No Ester).

Such hypocrisy should be avoided.
 
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  Some recent studies that report detrimental effects:

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