Winstrol will also drastically reduce HDL cholesterol levels and increase LDL levels which will bump up your blood pressure. Testosterone levels won't shut down completely from taking winny, but some bodybuilder like to combine it with testosterone because your natty production of test will be low after your cycle. To prevent yourself from experiencing low T, it'd be ideal to run testosterone as your coming off winstrol to keep this muscle-building hormone high. This will also help cement your gains, helping you hang on to the muscle you've gained on winny.
Trenbolone is derived from 19-nor Testosterone, but with three additional bonds- making it unable to aromatize (convert) to estrogen, as well as making it not subject to 5a-reduction (conversion to a Dihydro form). Speaking from a structural standpoint, Trenbolone is actually very similar to Deca-Durabolin (Nandrolone Decanoate), except for a c-9 and c-11 double bond. These two double bonds are very important, however, and provide Trenbolone with several important differences. Firstly, the c9 bond serves to prevent aromatization (conversion) to estrogen, while the c11 double bond seems to increase Androgen Receptor binding quite profoundly (although this may also have something to do with the c9 bond as well). Thus, as compared with Deca, Trenbolone’s lack of estrogenic activity and potent ability to bind to the androgen receptor allow it to be a much stronger anabolic/androgenic agent than Deca Durabolin. So what we see in Trenbolone is a drug that’s roughly 4x as anabolic as Deca, and roughly 10x as androgenic (according to the Vida Reference scale). With Trenbolone, the majority of weight gained on this drug is lean and quality muscle.