Bilirubin is a breakdown product of hemoglobin. Red blood cells contain hemoglobin, which is broken down into the components "heme" and "globin." Heme is converted into bilirubin. Albumin carries bilirubin to the liver, where most of it is conjugated with a glucuronide before it is excreted in the bile. Conjugated bilirubin is called "direct bilirubin;" unconjugated bilirubin is called "indirect bilirubin." Total bilirubin equals direct bilirubin plus indirect bilirubin.
Testosterone has been subject to abuse, typically at doses higher than recommended for approved indication and in combination with other anabolic androgenic steroids; anabolic androgenic steroid abuse can lead to serious cardiovascular and psychiatric adverse reactions; if testosterone abuse suspected, check serum testosterone concentrations to ensure they are within therapeutic range; consider possibility of testosterone and anabolic androgenic steroid abuse in suspected patients who present with serious cardiovascular or psychiatric adverse events